Teenage male was afflicted with debilitating migraines for 4+ years. Numerous treatment options were attempted using both drugs and natural medicine and nothing made any significant improvement in reduction of daily migraines frequently at 8/10 pain levels. We proposed a theory to a visiting Professor and he supported our treatment plan. Within a month of high dose nutrient therapy headaches went from 8/10 to 1/10. Pain levels continue to be managed with appropriate supplementation.